Inserting bone marrow cells into an individual who produces abnormal erythrocytes is an example of _____ therapy.
What is the role of DNA polymerase in DNA replication?
Transcription is best defined as a process by:
The purpose of a staining technique of chromosomes such as Giemsa is to:
An amniocentesis indicates a neural tube defect when there is an increase in:
An amniocentesis is recommended for pregnant women who
The most clinically useful technique for prenatal diagnosis of chromosomal abnormalities at 3 months’ gestation is:
The term for an error in which homologous chromosomes fail to separate during meiosis or mitosis is:
Which clinical manifestations would be expected for a child who has complete trisomy of the twenty-first chromosome?
What is the most common cause of Down syndrome?
What is the diagnosis of a 13-year-old female who has a karyotype that reveals an absent homologous X chromosome with only a single X chromosome present with features that include a short stature, widely spaced nipples, reduced carrying angle at the elbow, and sparse body hair?
A person with XXXY has the genetic disorder called __________ syndrome.
What is the chromosomal variation that causes Klinefelter syndrome?
What is the second most commonly recognized genetic cause of mental retardation?
What is the blood type of a person who is heterozygous, having A and B alleles as codominant?
A couple has two children with a genetic disease. What is the probability that the next child will have the same genetic disease?
People who have neurofibromatosis have a varying degree of the condition because of what genetic principle?
Which genetic disease has been linked to a mutation of the tumor-suppressor gene?
Cystic fibrosis is caused by a/an __________________ gene.
Which is an important criterion for discerning autosomal recessive inheritance?
Consanguinity refers to the mating of:
A genetically normal male is always _____________ for genes on the X chromosome.
Which of the following disorders has a mode of inheritance similar to hemophilia A?
If a boy has hemophilia A, he inherited it from:
A boy, 9 years of age, is admitted to the pediatric ward with hemophilia A. He inherited this condition through a ___________ trait.
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases
The data reporting that sickle cell disease affects approximately 1 in 600 American blacks is an example of which concept?
The _____ risk of developing a disease is expressed as the ratio of the disease rate among the exposed population to the disease rate in an unexposed population.
Empirical risks for most multifactorial diseases are based on:
What is the cause of familial hypercholesterolemia (FH)?
Which risk factor for hypertension is influenced by genetic factors and lifestyle?
An autosomal dominant form of breast cancer accounts for ____% of all cases.
If a woman has one first-degree relative with breast cancer, her risk of developing breast cancer is _____ times what it would otherwise be.
Cancers that cluster strongly in families include:
Which genes are responsible for an autosomal dominant form of breast cancer?
The BRCA1 and BRCA2 mutations increase the risk of which cancer in women?
What is the action of angiotensin II that increases blood pressure?
The two most important risk factors for type 2 diabetes are:
A major characteristic of type 1 diabetes mellitus is that there is:
Obesity acts as an important risk factor for type 2 diabetes mellitus by:
Studies have identified several genes that play a role in the prevention of obesity by:
Studies have shown that offspring of an alcoholic parent when raised by nonalcoholic parents have _____ increased risk of developing alcoholism.
Chapter 06: Epigenetics and Disease
What genetic process is likely responsible for the occurrence of asthma in only one of a pair of identical twins?
Prader-Willi syndrome causes a chromosomal defect that is:
A malfunction in DNA methylation can lead to:
What are some characteristics of the embryonic development of stem cells?
When microRNA (miRNA) are methylated, their messenger RNA (mRNA) targets are over-expressed. The resulting effect on existing cancer would be:
The difference between DNA sequence mutations and epigenetic modifications is:
Which term refers to the silenced gene of a gene pair?
The shape of the face of a child diagnosed with Russell-Silver syndrome is likely to be:
Genes responsible for the maintenance of all cells are referred to as:
What is the belief regarding twins who adopt dramatically different lifestyles?
Hypomethylation and the resulting effect on oncogenes result in a/an:
When a chromosome lacking 4 Mb is inherited from the mother, the child is at risk for developing which syndrome?
What are the physical characteristics of a child diagnosed with Beckwith-Wiedemann syndrome?
What are the physical characteristics of a child diagnosed with Angelman syndrome?